Genetic Separation of Listeria monocytogenes Causing Central Nervous System Infections in Animals
نویسندگان
چکیده
منابع مشابه
Genetic Separation of Listeria monocytogenes Causing Central Nervous System Infections in Animals
Listeria monocytogenes is a foodborne pathogen that causes abortion, septicemia, gastroenteritis and central nervous system (CNS) infections in ruminants and humans. L. monocytogenes strains mainly belong to two distinct phylogenetic groups, named lineages I and II. In general, clinical cases in humans and animals, in particular CNS infections, are caused by lineage I strains, while most of the...
متن کاملTargeting of the central nervous system by Listeria monocytogenes
Among bacteria that reach the central nervous system (CNS), Listeria monocytogenes (Lm) is one of deadliest, in human and ruminant. This facultative intracellular bacterium has the particularity to induce meningitis, meningoencephalitis and rhombencephalitis. Mechanisms by which Lm accesses the CNS remain poorly understood, but two major routes of infection have been proposed, based on clinical...
متن کاملCentral nervous system infections.
Central nervous system infections have long been recognized as among the most devastating of diseases. This article describes the changing pattern and epidemiology of a variety of common central nervous system infections, including meningitis, encephalitis, and brain abscesses, and reviews pathophysiology and the most current approach to clinical diagnosis, treatment, and disposition from the e...
متن کاملListeria monocytogenes infections
1. Historical aspects and contemporary problems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .313 2. Characteristics of Listeria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .314 3. Nature of infection in man and animals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .320 4. Pr...
متن کاملListeria monocytogenes-infected bone marrow myeloid cells promote bacterial invasion of the central nervous system.
Listeria monocytogenes is a facultative intracellular pathogen that is able to invade the central nervous system causing meningoencephalitis and brain abscesses. The mechanisms allowing bacteria to cross the blood-brain barrier are poorly understood. In this work, we used an experimental model of acute listeriosis in the mouse inducing a reproducible invasion of the central nervous system. At t...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2018
ISSN: 2235-2988
DOI: 10.3389/fcimb.2018.00020